dual specificity protein phosphatase 8 (dual-specificity phosphatase hVH-5, homolog of vaccinia virus H1 phosphatase, DUSP8, VH5)

Function

• dual specificity protein phosphatase

protein tyrosine phosphate + H2O
            <-->
protein tyrosine + phosphate

a phosphoprotein + H2O <--> a protein + phosphate

Structure

• belongs to the protein-tyrosine phosphatase family non-receptor class dual specificity subfamily
• contains 1 rhodanese domain
• contains 1 tyrosine-protein phosphatase domain

Compartment

cytoplasm (putative), nucleus

Expression

abundant in brain, heart & skeletal muscle

More general terms

• dual specificity phosphatase

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1850
• OMIM: https://mirror.omim.org/entry/602038
• UniProt: http://www.uniprot.org/uniprot/Q13202.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1850