dual specificity protein phosphatase 5 (dual specificity phosphatase B23, dual-specificity phosphatase hVH-3, VH-1-like protein tyrosine phosphatase, DUSP5, VH3)

Function

• displays phosphatase activity toward several substrates
• highest relative activity is toward ERK1

protein tyrosine phosphate + H2O
              <-->
protein tyrosine + phosphate

phosphoprotein + H2O <--> a protein + phosphate

Structure

• belongs to the protein-tyrosine phosphatase family non-receptor class dual specificity subfamily
• contains 1 rhodanese domain
• contains 1 tyrosine-protein phosphatase domain

Compartment

nucleus (putative)

More general terms

• dual specificity phosphatase

Database

• OMIM: https://mirror.omim.org/entry/603069
• UniProt: http://www.uniprot.org/uniprot/Q16690.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1847