protein phosphatase-2C beta; protein phosphatase 1B; protein phosphatase magnesium-dependent 1 beta (PPM1B, PP2CB)

Function

• protein phosphatase with broad specificity
• dephosphorylates CDK2 & CDK6 in vitro

Cofactor: binds 2 Mg+2 or Mn+2 per subunit

Structure

• monomer (putative)
• belongs to the PP2C family

Alternative splicing

named isoforms=2

Expression

highly expressed in heart & skeletal muscle

More general terms

• protein phosphatase-2C

Database

• OMIM: https://mirror.omim.org/entry/603770
• UniProt: http://www.uniprot.org/uniprot/O75688.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5495