tumor necrosis factor receptor superfamily member 13C; B cell-activating factor receptor; BAFF receptor; BAFF-R; BLyS receptor 3; CD268 (TNFRSF13C, BAFFR, BR3)

Function

• B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS
• promotes the survival of mature B-cells & the B-cell response

Structure

contains 1 TNFR-Cys repeat

Compartment

membrane

Alternative splicing

named isoforms=2

Expression

• highly expressed in spleen & lymph node, & in resting B-cells
• detected at lower levels in activated B-cells, resting CD4+ T-cells, in thymus & peripheral blood leukocytes

More general terms

• tumor necrosis factor [TNF] receptor family
• CD antigen

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1156
• OMIM: https://mirror.omim.org/entry/606269
• UniProt: http://www.uniprot.org/uniprot/Q96RJ3.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=115650