NO synthase-2B (inducible, NOS2B)
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Function
- produces nitric oxide (NO), a messenger molecule with diverse functions throughout the body
- in macrophages, NO mediates tumoricidal & bactericidal actions
L-arginine + n NADPH + m O2 <--> citrulline + nitric oxide + n NADP+
Cofactor:
- heme group (putative)
- binds 1 FAD (putative)
- binds 1 FMN (putative)
- tetrahydrobiopterin (BH4)
Structure
belongs to the NOS family
Notes
Could be the product of a pseudogene
More general terms
Additional terms
References
- ↑ UniProt http://www.uniprot.org/uniprot/P81272.html
- ↑ OMIM https://mirror.omim.org/entry/600719
- ↑ Wikipedia; Note: Nitric oxide synthase entry http://en.wikipedia.org/wiki/Nitric_oxide_synthase