homeobox protein HOX-B13 (HOXB13)

Function

• sequence-specific transcription factor
• part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis

Structure

• belongs to the Abd-B homeobox family
• contains 1 homeobox DNA-binding domain

Compartment

nucleus

Pathology

• variations in the HOXB13 gene are associated with susceptibility to prostate cancer

Laboratory

• HOXB13/IL17BR gene ratio

More general terms

• homeobox protein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1048
• OMIM: https://mirror.omim.org/entry/604607
• UniProt: http://www.uniprot.org/uniprot/Q92826.html