homeobox protein HOX-B1; HOX-2I (HOXB1, HOX2I)

Function

• sequence-specific transcription factor
• part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis
• acts on the anterior body structures

Structure

• belongs to the antp homeobox family, Labial subfamily
• contains 1 homeobox DNA-binding domain

Compartment

nucleus

Polymorphism

• two common alleles; HOX1B*A (78.8%) & HOX1B*B (21.2%)

More general terms

• homeobox protein

Database

• UniProt: http://www.uniprot.org/uniprot/P14653.html
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:3211
• OMIM: https://mirror.omim.org/entry/142968
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3211