ATP-binding cassette sub-family D member 2; adrenoleukodystrophy-related protein; hALDR; adrenoleukodystrophy-like 1 (ABCD2, ALD1, ALDL1, ALDR, ALDRP)

Function

• probable transporter
• can form heterodimers with ABCD1/ALD & ABCD3/PMP70
• dimerization is necessary to form an active transporter
• interacts with PEX19

Structure

• belongs to the ABC transporter family, ALD subfamily
• contains 1 ABC transmembrane type-1 domain
• contains 1 ABC transporter domain

Compartment

peroxisome membrane

Expression

predominantly expressed in brain & heart

More general terms

• ATP-binding cassette sub-family D (ABC transporter-D, ABCD)
• glycoprotein

Additional terms

• ABCD2 score

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:225
• OMIM: https://mirror.omim.org/entry/601081
• UniProt: http://www.uniprot.org/uniprot/Q9UBJ2.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=225