ATP-binding cassette sub-family B member 10, mitochondrial; ATP-binding cassette transporter 10; ABC transporter 10 protein; mitochondrial ATP-binding cassette 2; M-ABC2 (ABCB10)

Function

• may mediate mitochondrial transport functions related to heme biosynthesis

Structure

• homodimer or heterodimer (putative)
• belongs to the ABC transporter family, mitochondrial
• peptide exporter (TC 3.A.1.212) subfamily
• contains 1 ABC transmembrane type-1 domain
• contains 1 ABC transporter domain

Compartment

mitochondrial inner membrane

Expression

• ubiquitous
• expressed in bone marrow > skeletal muscle, small intestine, thyroid, heart, brain, placenta, liver, pancreas, prostate, testis, ovary, leukocyte, stomach, spinal cord, lymph nodes, trachea & adrenal gland > lung, kidney, spleen, thymus & colon

More general terms

• ATP-binding cassette sub-family B (ABC transporter-B, ABCB)

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2345
• OMIM: https://mirror.omim.org/entry/605454
• UniProt: http://www.uniprot.org/uniprot/Q9NRK6.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=23456