calmodulin-like protein 5 (calmodulin-like skin protein, CALML5, CLSP)
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Function
- binds Ca+2
- role in terminal differentiation of keratinocytes (putative)
- associates with transglutaminase 3
Structure
- contains 4 EF-hand domains
Expression
- particularly abundant in the epidermis where its expression is directly related to keratinocyte differentiation
- very low expression in lung