sorting nexin-15 (SNX15)

Function

• may be involved in several stages of intracellular trafficking
• overexpression of SNX15 disrupts the normal trafficking of proteins from the plasma membrane to recycling endosomes or the trans-Golgi network (TGN)

Structure

• belongs to the sorting nexin family
• contains 1 MIT domain
• contains 1 PX (phox homology) domain

Alternative splicing

named isoforms=2

Expression

widely expressed

More general terms

• sorting nexin
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=29907
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:29907
• OMIM: https://mirror.omim.org/entry/605964
• UniProt: http://www.uniprot.org/uniprot/Q9NRS6.html