cytochrome P450 1A1 (aryl hydrocarbon hydroxylase [AHH], cytochrome P450 C, CYPIA1, P450-P1)
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Function
- NADPH-dependent electron transport pathway
- oxidizes a variety of structurally unrelated compounds
Compartment
- endoplasmic reticulum membrane
- peripheral membrane
- microsome membrane
Expression
- lung, lymphocytes & placenta
- induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
More general terms
References
- ↑ UniProt http://www.uniprot.org/uniprot/P04798.html
- ↑ Cytochrome P450 Allele Nomenclature committee: CYP1A1 alleles http://www.cypalleles.ki.se/cyp1a1.htm
- ↑ SHMPD, The Singapore human mutation and polymorphism database http://shmpd.bii.a-star.edu.sg/gene.php?genestart=A&genename=CYP1A1
- ↑ Wikipedia; CYP1A1 entry http://en.wikipedia.org/wiki/CYP1A1