arginine decarboxylase; ADC; ARGDC; ODC-paralogue; ODC-p; ornithine decarboxylase-like protein (ADC KIAA1945 ODCP)

Function

• decarboxylates L-arginine to agmatine
• truncated splice isoforms probably lack activity

L-arginine <--> agmatine + CO2

Cofactor: pyridoxal phosphate (putative)

Structure

• belongs to the orn/Lys/Arg decarboxylase class-II family

Alternative splicing

• named isoforms=5
• additional isoforms seem to exist

Expression

• highly expressed in brain
• also expressed in testis

More general terms

• carboxy-lyase or decarboxylase

Additional terms

• ornithine decarboxylase 1

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=113451
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:113451
• OMIM: https://mirror.omim.org/entry/608353
• UniProt: http://www.uniprot.org/uniprot/Q96A70.html