D-dopachrome decarboxylase; D-dopachrome tautomerase; phenylpyruvate tautomerase 2 (DDT)

Function

• tautomerization of D-dopachrome with decarboxylation to yield 5,6-dihydroxyindole

D-dopachrome <--> 5,6-dihydroxyindole + CO2

Structure

• homotrimer
• belongs to the MIF family

Compartment

cytoplasm (putative)

More general terms

• carboxy-lyase or decarboxylase

Additional terms

• L-dopachrome tautomerase; DCT; DT; L-dopachrome delta-isomerase; tyrosinase-related protein 2; TRP-2; TRP2 (DCT, TYRP2)

Database

• UniProt: http://www.uniprot.org/uniprot/P30046.html
• OMIM: https://mirror.omim.org/entry/191275
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1652
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1652
• OMIM: https://mirror.omim.org/entry/602750