E3 ubiquitin-protein ligase RNF25 (RING finger protein 25, RNF25)

Function

• E2-dependent E3 ubiquitin-protein ligase activity
• ubiquitin conjugation, 3r step
• binds ubiquitin-conjugating enzymes (E2s)
• RING-type zinc finger domain interacts with an E2 ubiquitin-conjugating enzyme & facilitates ubiquitination.
• substrate for E2-dependent ubiquitination

Structure

• contains 1 RING-type zinc finger
• contains 1 RWD domain

More general terms

• E3 ubiquitin ligase
• ring finger protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q96BH1.html