tubulin polyglutamylase TTLL6 (tubulin-tyrosine ligase-like protein 6, TTLL6, TTL6)

Function

• polyglutamylase which preferentially modifies alpha-tubulin
• involved in the side-chain elongation step of the polyglutamylation reaction rather than in the initiation step

Structure

• belongs to the tubulin-tyrosine ligase family
• contains 1 TTL domain

Compartment

• cell projection, cilium, cilium basal body (putative)

Alternative splicing

named isoforms=2

More general terms

• tubulin polyglutamylase

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:2840
• UniProt: http://www.uniprot.org/uniprot/Q8N841.html