tRNA pseudouridine synthase 1 (TRUB1, PUS4)

Function

• may be responsible for synthesis of pseudouridine from uracil in transfer RNAs (putative)

tRNA uridine <--> tRNA pseudouridine

Structure

belongs to the pseudouridine synthase truB family

Expression

• highly expressed in heart, skeletal muscle & liver
• expressed at lower levels in lung, small intestine, kidney & spleen

More general terms

• tRNA pseudouridine synthase

Database

• UniProt: http://www.uniprot.org/uniprot/Q8WWH5.html