leucine carboxyl methyltransferase 2; p21WAF1/CIP1 promoter-interacting protein; tRNA wybutosine-synthesizing protein 4 homolog; tRNA yW-synthesizing protein 4 homolog (LCMT2, KIAA0547, TYW4)

Function

• probable S-adenosyl-L-methionine dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway
• methylates carboxyl group of Leu to form alpha-leucine ester residues
• interacts with IBRDC2

Structure

• belongs to the methyltransferase superfamily, LCMT family

More general terms

• methyltransferase

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9836
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:9836
• OMIM: https://mirror.omim.org/entry/611246
• UniProt: http://www.uniprot.org/uniprot/O60294.html