Glycosyltransferase-like protein LARGE2 (glycosyltransferase-like 1B, GYLTL1B, LARGE2, PP5656)

Function

• glycosyltransferase
• role in glycosylation of alpha-dystroglycan
• may carry out synthesis of glycoprotein & glycosphingolipid sugar chains
• higher activity toward alpha-dystroglycan than LARGE

Structure

belongs to the glycosyltransferase 8 family

Compartment

• Golgi membrane

Alternative splicing

named isoforms=2

Expression

• widely expressed
• expressed at high level in placenta, pancreas & kidney compared to LARGE
• not expressed in brain

More general terms

• glycosyltransferase

Database

• UniProt: http://www.uniprot.org/uniprot/Q8N3Y3.html