saccharopine dehydrogenase SCCPDH (SCCPDH)

Function

• Lysine degradation; Saccharopine pathway; 2nd step

N(6)-(L-1,3-dicarboxypropyl)-L-lysine + NAD+ + H2O <--> L-glutamate + 2-aminoadipate 6-semialdehyde + NADH

Structure

belongs to the saccharopine dehydrogenase family

More general terms

• dehydrogenase

Additional terms

• alpha-aminoadipic semialdehyde synthase, mitochondrial; LKR/SDH; includes: lysine ketoglutarate reductase; LKR; LOR; saccharopine dehydrogenase; SDH (AASS)

Database

• UniProt: http://www.uniprot.org/uniprot/Q8NBX0.html