UDP-glucose 6-dehydrogenase; UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH (UGDH)

Function

• biosynthesis of glycosaminoglycans
  • hyaluronan, chondroitin sulfate, heparan sulfate
• nucleotide-sugar biosynthesis
  • UDP-alpha-D-glucuronate biosynthesis
    • UDP-alpha-D-glucuronate from UDP-alpha-D-glucose
      • step 1/1

Structure

• homohexamer (putative)
• belongs to the UDP-glucose/GDP-mannose dehydrogenase family

Expression

widely expressed

More general terms

• dehydrogenase
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7358
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:7358
• OMIM: https://mirror.omim.org/entry/603370
• UniProt: http://www.uniprot.org/uniprot/O60701.html