inositol oxygenase; aldehyde reductase-like 6; kidney-specific protein 32; myo-inositol oxygenase; MI oxygenase; renal-specific oxidoreductase (MIOX, ALDRL6, KSP32, RSOR)

Function

• polyol metabolism
  • myo-inositol degradation into D-glucuronate
  • D-glucuronate from myo-inositol: step 1/1

Cofactor: binds 2 iron ions per subunit

Structure

• belongs to the myo-inositol oxygenase family

Compartment

cytoplasm (putative)

Alternative splicing

named isoforms=2

Expression

kidney specific

More general terms

• oxygenase

Additional terms

• inositol

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=55586
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:55586
• OMIM: https://mirror.omim.org/entry/606774
• UniProt: http://www.uniprot.org/uniprot/Q9UGB7.html