junctional adhesion molecule C; JAM-C; JAM-2; junctional adhesion molecule 3; JAM-3 (JAM3)

Function

• may participate in cell-cell adhesion distinct from tight junctions
• interacts with JAM2

Structure

• belongs to the immunoglobulin superfamily
• contains 1 Ig-like C2-type domain
• contains 1 Ig-like V-type domain

Compartment

• cell membrane; single-pass type 1 membrane protein (putative)

Expression

• widely expressed
• highest expression in placenta, brain & kidney

More general terms

• junctional adhesion molecule

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=83700
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:83700
• OMIM: https://mirror.omim.org/entry/606871
• UniProt: http://www.uniprot.org/uniprot/Q9BX67.html