contactin-3; brain-derived immunoglobulin superfamily protein 1; BIG-1; plasmacytoma-associated neuronal glycoprotein (CNTN3, KIAA1496, PANG)
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Function
- contactins mediate cell surface interactions during nervous system development.
- some neurite outgrowth-promoting activity
- interacts with PTPRG
Structure
- belongs to the immunoglobulin superfamily, contactin family
- contains 4 fibronectin F3 modules
- contains 6 Ig-like C2-type domains (immunoglobulin-like)
Compartment
- cell membrane, lipid-anchor, GPI-anchor
Expression
- in brain, it is expressed in frontal lobe, occipital lobe, cerebellum, amygdala