kinesin family member 17 (Kif17, KIF3-related motor protein)

Function

• microtubule-dependent, neuron-specific molecular motor
• apparently, functions as a dendritic motor (see OMIM :accession 605037)
• transports vesicles containing N-methyl-D-aspartate (NMDA) receptor 2B along microtubules (putative)
• interacts with LIN-10 PDZ domain (putative)

Structure

• homodimer
• belongs to the kinesin-like protein family
• contains 1 kinesin-motor domain

Alternative splicing

named isoforms=2

Expression

• expressed in gray matter, especially the hippocampus, but not in white matter

More general terms

• kinesin family protein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5757
• OMIM: https://mirror.omim.org/entry/605037
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=57576
• UniProt: http://www.uniprot.org/uniprot/Q9P2E2.html