rab5c proto-oncogene protein; Ras-related protein Rab-5C; RAB5L; L1880 (RAB5C, RABL)

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Function

plasma membrane-early endosome transport
early endosome fusion & mobility
probably involved in vesicular traffic (putative)
binds EEA1

Structure

belongs to the small GTPase superfamily, Rab family

Compartment

cell membrane; lipid-anchor; cytoplasmic side (putative).
early endosome membrane; lipid-anchor
melanosome; stage I to stage IV

More general terms

rab5 proto-oncogene protein

References

↑ UniProt http://www.uniprot.org/uniprot/P51148.html
↑ Seabra MC et al Rab GTPases, intracellular traffic and disease Trends in Molecular Medicine 8:23, 2002 PMID: https://www.ncbi.nlm.nih.gov/pubmed/11796263
↑ Entrez Gene http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5878

Database

UniProt: http://www.uniprot.org/uniprot/P51148.html
Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5878
Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5878
OMIM: https://mirror.omim.org/entry/604037

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