AP-2 complex subunit sigma-1; adaptor protein 17; adaptor-related protein complex 2 sigma-1 subunit; sigma2-adaptin; plasma membrane adaptor AP-2 17 kD protein; HA2 17 kD subunit; clathrin assembly protein 2 small chain; clathrin coat assembly protein AP17; clathrin coat-associated protein AP17 (AP2S1, AP17, CLAPS2)

Function

• one of 4 subunits of clathrin assembly protein complex 2 (AP-2)

Structure

belongs to the adaptor complexes small subunit family

Compartment

• cell membrane, coated pit
• peripheral membrane, cytoplasmic side
• component of coat surrounding the cytoplasmic face of coated vesicles in the plasma membrane

Alternative splicing

named isoforms=2

More general terms

• sigma adaptin

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1175
• OMIM: https://mirror.omim.org/entry/602242
• UniProt: http://www.uniprot.org/uniprot/P53680.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1175