phosphatidylinositol-glycan biosynthesis class W protein ( PIG-W, PIGW)

Function

• probable acetyltransferase
• acetylates inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor
• acetylation during GPI-anchor biosynthesis is not essential for the subsequent mannosylation & is usually removed soon after the attachment of GPIs to proteins (putative)
• glycolipid biosynthesis; GPI-anchor biosynthesis

Structure

belongs to the PIGW family

Compartment

endoplasmic reticulum membrane

More general terms

• acetyltransferase
• transmembrane 12e protein

Database

• UniProt: http://www.uniprot.org/uniprot/Q7Z7B1.html