CMP-sialic acid transporter (CST, CMP-Sia-Tr, CMP-SA-Tr, solute carrier family 35 member 1, SLC35A1)

Function

• transports CMP-sialic acid from cytosol into Golgi vesicles where glycosyltransferases function

Structure

• belongs to the nucleotide-sugar transporter family SLC35A subfamily

Compartment

Golgi apparatus membrane

Pathology

• defects in SLC35A1 are the cause of congenital disorder of glycosylation type 2F

More general terms

• solute carrier family 35
• transmembrane 7 protein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1055
• OMIM: https://mirror.omim.org/entry/603585
• OMIM: https://mirror.omim.org/entry/605634
• UniProt: http://www.uniprot.org/uniprot/P78382.html