transmembrane cochlear-expressed protein 1; transmembrane channel-like protein 1 (TMC1)
Jump to navigation
Jump to search
Function
- involved in normal function of cochlear hair cells
- forms the pore that carries hair cell signals[2]
Structure
belongs to the TMC family
Compartment
membrane (putative)
Expression
expressed in fetal cochlea > placenta, testis
Pathology
- defects in TMC1 are associated with
More general terms
References
- ↑ UniProt http://www.uniprot.org/uniprot/Q8TDI8.html
- ↑ 2.0 2.1 Pan B, Akyuz N, Liu XP, et al. TMC1 forms the pore of mechanosensory transduction channels in vertebrate inner ear hair cells. Neuron 2018 Aug 22; 99:736 PMID: https://www.ncbi.nlm.nih.gov/pubmed/30138589
Database
- Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=117531
- Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:117531
- OMIM: https://mirror.omim.org/entry/600974
- OMIM: https://mirror.omim.org/entry/606705
- OMIM: https://mirror.omim.org/entry/606706
- UniProt: http://www.uniprot.org/uniprot/Q8TDI8.html