ARL-6-interacting protein 1; ADP-ribosylation-like factor 6-interacting protein 1; Aip-1 (ARL6IP, ARL6IP1, KIAA0069)
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Function
- protein transport, membrane trafficking, or cell signaling during hematopoietic maturation
- interacts with ARL6
Compartment
intracytoplasmic membrane
Expression
- expressed in all hematopoietic cell lineages
- highest expression in early myeloid progenitor cells > brain, bone marrow, thymus, lung > liver, kidney, spleen
- not expressed in heart
- down-regulated during myeloid differentiation