protein C17orf28; down-regulated in multiple cancers-1 (HID1, C17orf28, DMC1)

Function

• role in the development of cancers in a broad range of tissues

Compartment

membrane

Alternative splicing

named isoforms=3

Expression

• expressed in heart, skeletal muscle, colon, spleen, kidney, liver, small intestine & lung
• highest expression in brain & placenta

Pathology

• loss of expression in some breast, cervical, hepatocellular, lung, thyroid, gastric & renal cell-cancer lines

More general terms

• transmembrane 2 protein

Database

• OMIM: https://mirror.omim.org/entry/605752
• UniProt: http://www.uniprot.org/uniprot/Q8IV36.html