ectonucleoside triphosphate diphosphohydrolase 3; NTPDase 3; CD39 antigen-like 3; ecto-ATP diphosphohydrolase 3; ecto-ATPDase 3; ecto-ATPase 3; ecto-apyrase 3; HB6 (ENTPD3, CD39L3)

Function

• 3-fold preference for hydrolysis of ATP over ADP

Cofactor: Ca+2, Mg+2

Structure

belongs to the GDA1/CD39 NTPase family

Compartment

membrane (potential)

Expression

• expressed in adult brain, pancreas, spleen & prostate
• moderate or low expression is seen in most tissues
• not expressed in liver or peripheral blood leukocytes

More general terms

• CD39 like protein
• transmembrane 2 protein

Additional terms

• CD39; ectonucleoside triphosphate diphosphohydrolase 1; NTPDase 1; ecto-ATP diphosphohydrolase; ATPDase; lymphoid cell activation antigen; ecto-apyrase (ENTPD1)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=956
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:956
• OMIM: https://mirror.omim.org/entry/603161
• UniProt: http://www.uniprot.org/uniprot/O75355.html