mucin-19 (MUC-19, MUC19)

Function

may function in ocular mucus homeostasis

Structure

• contains 1 CTCK (C-terminal cystine knot-like) domain
• contains 2 VWFC domains
• contains 3 VWFD domains

Compartment

secreted (putative)

Alternative splicing

named isoforms=2

Expression

• expressed corneal epithelial cells, conjunctival goblet & epithelial cells & lacrimal gland cells (at protein level)
• expressed by mucous cells of the submandibular gland & submucosal gland of the trachea
• expressed by middle ear epithelial cells

Pathology

• down-regulated in Sjoegren syndrome patients (at protein level)

More general terms

• mucin

Database

• UniProt: http://www.uniprot.org/uniprot/Q7Z5P9.html
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=283463