mucin-13 (down-regulated in colon cancer 1, MUC13, DRCC1, RECC, UNQ6194/PRO20221)

Function

• epithelial & hemopoietic transmembrane mucin
• cell signaling (putative)

Structure

• cleaved into 2 subunits, alpha & beta
• beta subunit contains cytoplasmic tail
• alpha subunit contains extracellular tail
• intermolecular disulfide bonds
• highly N-glycosylated
• homodimer of beta subunits may occur

Compartment

cell membrane, secreted protein

Expression

• highly expressed in epithelial tissues (GI & respiratory tracts)
• expressed in colon, trachea > kidney, small intestine, appendix, stomach

More general terms

• mucin

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=56667
• UniProt: http://www.uniprot.org/uniprot/Q9H3R2.html