apolipoprotein L4; apoL-IV (APOL4)

Function

• may play a role in lipid exchange & transport throughout the body
• may participate in reverse cholesterol transport from peripheral cells to the liver

Structure

belongs to the apolipoprotein L family

Compartment

secreted (putative)

Alternative splicing

named isoforms=3

Expression

• widely expressed
• highest levels in spinal cord, placenta, adrenal gland
• also detected in spleen, bone marrow, uterus, trachea, mammary gland & testis;
• low levels in brain, heart & pancreas

More general terms

• apolipoprotein L

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=80832
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:80832
• OMIM: https://mirror.omim.org/entry/607254
• UniProt: http://www.uniprot.org/uniprot/Q9BPW4.html