AT-rich interactive domain-containing protein 5B (ARID domain-containing protein 5B, Mrf1-like, modulator recognition factor 2, MRF-2, ARID5B, DESRT, MRF2)

Function

• DNA-binding protein, via ARID domain
• binds to the 5'-AATA[CT]-3 core sequence
• transcription regulator (putative)
• regulator of smooth muscle cell differentiation & proliferation (putative)
• role in lipid stores (putative)
  • may be inhibited by protein fatso (FTO)

Structure

• contains 1 ARID domain

Compartment

nucleus

Alternative splicing

named isoforms=2

Pathology

• expresses the cytomegalovirus enhancer

More general terms

• AT-rich interactive domain-containing protein

Database

• OMIM: https://mirror.omim.org/entry/608538
• UniProt: http://www.uniprot.org/uniprot/Q14865.html