ATP-dependent RNA helicase DDX12; DEAD/H box protein 12; CHL1-related protein 2; hCHLR2 (DDX12, CHLR2, DDX12P)

Function

• DNA helicase involved in cellular proliferation
• probably required for maintaining the chromosome segregation

Structure

• belongs to the DEAD box helicase family, DEAH subfamily, DDX11/CHL1 sub-subfamily
• contains 1 helicase ATP-binding domain

Compartment

nucleus (putative)

Expression

Only expressed in proliferating tissues

More general terms

• helicase (DNA unwinding protein, DNA untwisting protein)

Database

• OMIM: https://mirror.omim.org/entry/601151
• UniProt: http://www.uniprot.org/uniprot/Q92771.html