ATP-dependent RNA helicase DDX11; CHL1-related protein 1; hCHLR1; DEAD/H box protein 11; keratinocyte growth factor-regulated gene 2 protein; KRG-2 (DDX11 CHL1 CHLR1 KRG2)

Function

• cellular proliferation (putative)
• may function during S phase, G2 phase, or M phase of the cell cycle
• binds to both ssDNA & dsDNA

Compartment

nucleus, nucleolus

Alternative splicing

named isoforms=5

Expression

• highly expressed in spleen, B-cells, thymus, testis, ovary, small intestine, pancreas
• very low expression in brain
• expressed in dividing cells &/or cells undergoing recombination
• No expression in cells committed to terminally differentiate

More general terms

• DEAH box ATP-dependent helicase

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1663
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1663
• OMIM: https://mirror.omim.org/entry/601150
• UniProt: http://www.uniprot.org/uniprot/Q96FC9.html