ATP-dependent RNA helicase DDX46; DEAD box protein 46; PRP5 homolog (DDX46, KIAA0801)

Function

• probable ATP-dependent RNA helicase
• role in splicing
• integral component of 17S U2 snRNP

Structure

• belongs to the DEAD box helicase family, DDX46/PRP5 subfamily
• contains 1 helicase ATP-binding domain
• contains 1 helicase C-terminal domain

Compartment

nucleus, nucleoplasm, nuclear speckle, Cajal body

More general terms

• helicase (DNA unwinding protein, DNA untwisting protein)
• phosphoprotein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9879
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:9879
• UniProt: http://www.uniprot.org/uniprot/Q7L014.html