beta-defensin 2; beta-defensin 4A; BD-2; hBD-2; defensin, beta 2; skin-antimicrobial peptide 1; SAP1 (DEFB4A, DEFB102, DEFB2, DEFB4, DEFB4B)

Function

• transcriptionally regulated antimicrobial peptide expressed in skin & respiratory tract
• has antibacterial activity (putative)

Structure

belongs to the beta-defensin family, LAP/TAP subfamily

Compartment

secreted

Expression

• expressed in the skin & respiratory tract
• induced by inflammation

More general terms

• beta defensin

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=100289
• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1673
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:100289
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1673
• OMIM: https://mirror.omim.org/entry/602215
• UniProt: http://www.uniprot.org/uniprot/O15263.html