hyaluronan & proteoglycan link protein 1; cartilage-linking protein 1; cartilage-link protein; proteoglycan link protein (HAPLN1, CRTL1)

Function

• stabilizes aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix

Structure

• belongs to the HAPLN family
• contains 1 Ig-like V-type domain
• contains 2 link domains

Compartment

• secreted, extracellular space, extracellular matrix

Expression

• widely expressed
• weakly expressed in brain

More general terms

• proteoglycan link protein; cartilage link protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1404
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1404
• OMIM: https://mirror.omim.org/entry/115435
• UniProt: http://www.uniprot.org/uniprot/P10915.html