dynein heavy chain 3, axonemal (ciliary dynein heavy chain 3, axonemal beta dynein heavy chain 3, HsADHC3, Dnahc3-b, DNAH3, DNAHC3B)

Function

• force generating protein of respiratory cilia
• involved in sperm motility
• implicated in sperm flagellar assembly (putative)

Structure

• belongs to the dynein heavy chain family
• contains 21 LRR repeats (leucine-rich repeats)

Compartment

cell projection, cilium axoneme (putative)

Alternative splicing

named isoforms=3

Expression

• expressed primarily in trachea & testis
• also expressed in lung

More general terms

• dynein heavy chain

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5556
• OMIM: https://mirror.omim.org/entry/603334
• UniProt: http://www.uniprot.org/uniprot/Q8TD57.html