dynein heavy chain 10, axonemal (ciliary dynein heavy chain 10, axonemal beta dynein heavy chain 10, DNAH10, KIAA2017)

Function

• probable inner arm dynein heavy chain
• force generating protein of respiratory cilia
• produces force towards the minus ends of microtubules
• involved in sperm motility
• implicated in sperm flagellar assembly (putative)

Structure

• belongs to the dynein heavy chain family
• contains 16 LRR repeats (leucine-rich repeats)
• contains 5 TPR repeats

Compartment

cell projection, cilium axoneme (putative)

Expression

• expressed primarily in trachea & testis
• also expressed in brain but not in adult heart

More general terms

• dynein heavy chain

Database

• OMIM: https://mirror.omim.org/entry/605884
• UniProt: http://www.uniprot.org/uniprot/Q8IVF4.html