SLIT & NTRK-like protein 6 (SLITRK6)

Function

• suppresses neurite outgrowth

Structure

• belongs to the SLITRK family
• contains 16 LRR repeats (leucine-rich repeats)

Compartment

membrane

Alternative splicing

named isoforms=2

Expression

• expressed in adult brain
• highly expressed in putamen
• no expression in cerebral cortex
• xpressed in adult fetal lung & fetal liver

Pathology

• expressed at high levels in some brain tumors, including medulloblastomas & primitive neuroectodermal tumors

More general terms

• SLIT & NTRK-like protein (SLITRK)

Database

• UniProt: http://www.uniprot.org/uniprot/Q9H5Y7.html