F-box only protein-47 (FBXO47)

Function

• recognizes & binds to some phosphorylated proteins & promotes their ubiquitination & degradation (By similarity).
• component of SCF complex

Structure

• contains 1 F-box domain

Expression

• widely expressed, highest levels in kidney, liver, pancreas

Pathology

• down-regulated in tumors

More general terms

• F-box only protein

Component of

• SCF-type E3 ligase complex

Database

• UniProt: http://www.uniprot.org/uniprot/Q5MNV8.html