sentrin-specific protease 7; SUMO-1-specific protease 2; sentrin/SUMO-specific protease SENP7 (SENP7, KIAA1707, SSP2, SUSP2)

Function

• protease that deconjugates SUMO2 & SUMO3 from targeted proteins
• does not deconjugate SUMO1
• catalyzes deconjugation of poly-SUMO2 & poly-SUMO3 chains
• has very low efficiency in processing full-length SUMO proteins to their mature forms

Structure

• belongs to the peptidase C48 family

Alternative splicing

named isoforms=5

More general terms

• sentrin-specific protease (SUMO-specific protease)
• phosphoprotein

Additional terms

• small ubiquitin-related modifier 1; SUMO-1; sentrin; ubiquitin-like protein SMT3C; SMT3 homolog 3; ubiquitin-homology domain protein PIC1; ubiquitin-like protein UBL1; GAP-modifying protein 1; GMP1 (SUMO1, SMT3C, SMT3H3, UBL1, OK/SW-cl43)

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=57337
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:57337
• OMIM: https://mirror.omim.org/entry/612846
• UniProt: http://www.uniprot.org/uniprot/Q9BQF6.html