ubiquitin carboxyl-terminal hydrolase 49; deubiquitinating enzyme 49; ubiquitin thiolesterase 49; ubiquitin-specific-processing protease 49 (USP49)

Function

• thiol-dependent hydrolysis of ester, thioester, amide, peptide & isopeptide bonds formed by the C-terminal Gly of ubiquitin

Structure

• belongs to the peptidase C19 family
• contains 1 UBP-type Zn+2 finger

Alternative splicing

named isoforms=2

More general terms

• ubiquitin C-terminal hydrolase
• zinc finger protein

Database

• Entrez gene: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=25862
• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:25862
• UniProt: http://www.uniprot.org/uniprot/Q70CQ1.html