Lysophosphatidic acid receptor 1; LPA receptor 1; LPA-1; Lysophosphatidic acid receptor Edg-2 (LPAR1, EDG2, LPA1)

Function

• receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities
• seems to be coupled to Gi proteins, Go proteins, G12 proteins, & Gq proteins

Structure

belongs to the G-protein coupled receptor 1 family

Compartment

cell membrane

Expression

• expressed in many adult organs, including brain, heart, colon, small intestine, placenta, prostate, ovary, pancreas, testes, spleen, skeletal muscle, & kidney
• little or no expression in liver, lung, thymus, or peripheral blood leukocytes

More general terms

• lysophosphatidic acid receptor (LPA-R)
• glycoprotein

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:1902
• OMIM: https://mirror.omim.org/entry/602282
• UniProt: http://www.uniprot.org/uniprot/Q92633.html