red-sensitive opsin; red cone photoreceptor pigment (OPN1LW, RCP)

Function

• component of visual pigment woth light absorption (max)=560 nm
• phosphorylated on some or all of the Ser & Thr present in the C-terminal region

Structure

• belongs to the G-protein coupled receptor 1 family opsin subfamily

Compartment

membrane

Expression

• the three color pigments are found in the cone photoreceptor cells

Pathology

• defects in OPN1LW are the cause of partial colorblindness protan series (protanopia)

More general terms

• opsin

Database

• Kegg: http://www.genome.jp/dbget-bin/www_bget?hsa:5956
• OMIM: https://mirror.omim.org/entry/303900
• UniProt: http://www.uniprot.org/uniprot/P04000.html